Опубликовано Monash University
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1. Determination of the dosage regimens of intravenous colistimethate in critically-ill patients is complicated, and requires thorough understanding of the pharmacokinetics of colistimethate and formed colistin and the confusing dose unit definitions in different parts of the world (Lancet Infect Dis.
2. Dis., 2017; 64:565-571), ColistinDose provides an accurate and easy tool to clinicians on calculating the dosage regimens of intravenous colistimethate in critically-ill patients with different renal function and those on renal replacement therapy.
3. For the convenience of clinicians in different regions of the world, all doses are provided with two commonly used conventions, i.e. colistin base activity (CBA) and international million unit (MU), to avoid the conversion.
4. ColistinDose is a clinician-friendly, easy-to-use iPhone app with the up-to-date dosing recommendations of intravenous colistimethate in critically-ill patients.
5. (3) Retrieval of historical calculation results, which allows clinicians to easily revisit previously calculated colistimethate doses and make appropriate dose adjustments.
6. ColistinDose features the following three major functionalities.
7. Integrating the state-of-the-art clinical pharmacokinetic/pharmacodynamic information (Clin.
8. It is intended for use by healthcare professionals only.
9. 2006; 6:589-601).
10. Infect.
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